Mufti Ismatullah did his PhD from Karachi University and his Takhassus (specialization) in Islamic Fiqh and Fatawa from Jamia Dar ul Uloom. He has extensive experience teaching various courses there. He has worked for over ten years in the Fatwa department (Darul Ifta) at Dar ul Uloom.

Besides being the Shariah Advisor at Pak-Qatar Family Takaful Limited and Pak-Qatar General Takaful Limited he also serves as the Shariah Advisor at Bank Al Habib's Islamic Banking Division.

Mufti Ismatullah is also involved in research in the fields of Islamic finance and specifically Takaful.